Vitamin B12 99% White Powder - Pure Cyanocobalamin for Supplementation
Introduction to Cyanocobalamin Science
Vitamin B12 in its cyanocobalamin form represents the most stable and widely utilized version of this essential water-soluble vitamin. Our 99% pure cyanocobalamin powder meets stringent pharmacopeial standards, offering manufacturers a bright red crystalline compound with exceptional purity and consistent biological activity. As the only vitamin containing cobalt, this complex molecule plays critical roles in neurological function, red blood cell formation, and DNA synthesis, making it indispensable for addressing global B12 deficiency and supporting comprehensive metabolic health.
Key Product Specifications
Chemical Name: α-(5,6-Dimethylbenzimidazolyl)cyanocobamide
Molecular Formula: C₆₃H₈₈CoN₁₄O₁₄P
Purity: ≥99% by HPLC
Appearance: Dark red crystalline powder
Solubility: 1.25g/100mL in water
Stability: 24 months when stored
Certifications: USP, EP, JP, FDA 21CFR184.1945 GRAS
Biological Functions & Clinical Significance
1. Hematopoietic Support
Essential for erythrocyte maturation
Prevents megaloblastic anemia
Works synergistically with folate metabolism
2. Neurological Maintenance
Myelin sheath synthesis
Neurotransmitter production
Cognitive function support
Peripheral nerve protection
3. Energy Metabolism
Methylmalonyl-CoA mutase cofactor
Mitochondrial energy production
Reduces fatigue and weakness
4. Specialized Applications
Homocysteine regulation
Methylation cycle support
DNA synthesis and repair
Detoxification pathways
Target Populations for Supplementation
Vegans/Vegetarians: Absent in plant foods
Elderly (50+ years): Impaired absorption
Pernicious Anemia Patients: Intrinsic factor deficiency
Gastrointestinal Disorders: Crohn's, celiac, post-surgical
Chronic Medication Users: Metformin, PPIs, nitrous oxide
Supplement & Clinical Applications
1. Oral Supplementation
Tablets (100-1000μg doses)
Sublingual formulations
Chewable and gummy formats
Multivitamin blends
2. Injectable Preparations
Therapeutic ampoules
B12 deficiency treatment
Neurological support
3. Specialized Nutrition
Infant formulas
Enteral/parenteral nutrition
Sports performance products
Geriatric formulations
Technical Advantages for Manufacturers
1. Enhanced Stability Profile
Superior to hydroxocobalamin in dry forms
Maintains potency in multivitamin blends
Withstands standard processing temperatures
2. Bioavailability Optimization
Efficient conversion to active coenzymes
Multiple absorption pathways
Predictable pharmacokinetics
3. Formulation Flexibility
Direct compression compatible
Soluble forms for liquid products
Microencapsulation options available
Quality & Safety Assurance
Global Regulatory Status
FDA: GRAS (21CFR184.1945)
EU: Approved nutrient
JP: Pharmacopeia standard
Codex: Included in NRVs
Safety Profile
No established UL (excess excreted)
Non-toxic at physiological doses
70+ years of therapeutic use
Quality Control Protocol
Identity confirmed by UV-Vis spectroscopy
Heavy metals
Cyanide content
Microbiological standards compliance
Usage Guidelines
Recommended Daily Intakes
Adults: 2.4μg
Pregnancy: 2.6μg
Lactation: 2.8μg
Therapeutic doses: 100-1000μg
Formulation Best Practices
Direct Compression: With suitable excipients
Liquid Systems: Pre-dissolution recommended
Protection: From light and moisture
Stability Considerations
Amber glass/opaque packaging
Storage below 25°C (77°F)
Avoid strong oxidizing agents
Why Choose Our Cyanocobalamin?
1. Scientific Validation
Batch-specific HPLC certification
Forced degradation studies
Bioavailability data
2. Technical Support
Stability testing protocols
Excipient compatibility
Regulatory documentation
3. Supply Chain Excellence
cGMP manufacturing
Temperature-controlled logistics
Global distribution network
Market Trends & Innovations
Vegan Nutrition: Plant-based delivery systems
Healthy Aging: Cognitive protection
Personalized Nutrition: Genetic polymorphism targeting
Advanced Delivery: Liposomal technologies
Sustainability Features
Responsible cobalt sourcing
Energy-efficient production
Reduced packaging waste
| Items | Specifications |
|---|---|
| Appearance | White or of- white powder or crystlline power,odorless |
| Solubility | Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water. |
| Melting Point | 152°C~156°C |
| PSA | 479.7 |
| XLogP3 | 6.57018 |
| Appearance | red crystalline powder |
| Melting Point | >300 °C |
| Boiling Point | >300 °C |
| Flash Point | 48.2°F |
| Water Solubility | Soluble |
| Storage Conditions | 2-8ºC |
| Toxicity | LD50 intravenous in mouse: 2gm/kg |
| Specific rotation | SPECIFIC OPTICAL ROTATION: -59 + or - 9 DEG @ 23 °C 656 NM (DILUTE AQ SOLN) |
| Odor | Odorless |
| Taste | Tasteless |
| PH | Commercially available cyanocobalamin for injection has a pH of 4.5-7 |
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| Established | December 18, 2014 | ||
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Beijing United Information Technology Co., Ltd. (Stock Code: 603613. SH), founded in 2002 and listed on the Main Board in July 2019, is mainly engaged in industrial e-commerce and industrial Internet platforms. Based on industrial e-commerce and supported by industrial big data and industrial digitalization, the company provides online commodity trading, business information services and digital technology services of industrial products and raw materials for related industries. In terms of business model, it is called "the industrial version of Pinduoduo" and "the industrial version of JD.com".
About Beijing TDD E-commerce Co., Ltd.
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Beijing TDD E-commerce Co., Ltd. (shortly named TDD Global) is the core subsidiary of Guolian Corporation (Stock Code: 603613.SH) and the first industrial Internetplatform of Duoduo Series Platforms. The company mainly engages in B28 e-commerce transaction serices of raw material and industrial products, digital supply chain serices, industrial digitalization serices and industrial big data serices, and is committed to promoting the deep integration of traditional industries and new technologies such as the Internet, Internet of Things, big data, intelligent manufacturing and block chain, etc.
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